Mindy Kaling

Once delegated to the role of adorable side character, Mindy Kaling is now a power player in Hollywood. In 2023, she lost around 40 pounds, saying she felt great, but she didn’t detail how she achieved it. She did mention that she loved running and hiking, doing up to 20 miles per week of one or the other. However, many say that to reach such results after years of battling your natural body type, Ozempic was the only way.

Jessica Simpson

This 90s and 2000s pop princess was once in the press for her catchy tunes, but once her heyday passed, she was in the tabloids for another reason—her appearance. Some of the comments were seriously cruel; despite still being gorgeous with some curves, she was judged for wearing “mom jeans” at a chili cook-off with a punny TMZ headline that read, “Jessica Simpson: This Is How She Rolls.” She spoke out about how hurtful the comments were and how they stayed with her, and years later, she’s significantly leaner. While she’s denied Ozempic, social media users speculated that she was on it and that it was getting too thin, which was the reason for her divorce.

Jesse Plemons

This actor told Entertainment Tonight that he lost 50 pounds over the course of a year and a half, and while a sleeker image was a benefit, the biggest pro was having more energy to keep up with his young kids. While he credited intermittent fasting as the backbone of his weight loss. He told the LA Times, “It’s really unfortunate that I decided to get healthy when everyone decided to take Ozempic. It doesn’t matter, everyone’s going to think I took Ozempic anyways.”

Kyle Richards

Members of the “Real Housewives” franchise are no strangers to nips, tucks, and weight loss hacks, and one of the most scrutinized is Kyle Richards of “The Real Housewives of Beverly Hills.” She’s managed to keep her physique lean over the 20 years she’s been in the spotlight, which has naturally led to GLP-1 speculation. Speaking of the rumors to Page Six, she said, “I had never heard of it. I had heard of it when they accused me, but I’d already lost weight by the time I had heard about Ozempic, so it was really frustrating to me.” Her daughter, Sophia, has admitted to taking Mounjaro and said she lost clumps of hair as a result.